Mesenteric ischemia is a medical condition in which inflammation and injury of the stomach and small or large bowel result from inadequate blood supply. Causes of the reduced blood flow can include changes in the systemic circulation or local factors such as constriction of blood vessels or a blood clot. Symptoms can vary from mild to moderate abdominal pain and weight loss to severe pain and bowel necrosis (gangrene) that can lead to death if untreated. Depending on the etiology and presentation, it can be treated with minimally invasive surgery (endovascular surgery which includes thrombolysis, angioplasty, stenting) or with open surgery (bypass or embolectomy).